Further observations on the effects of thyroid hormone preparations on cholesterolemia and atherogenesis in cholesterol-fed cockerels.

Failure of D- and L-thyroxine to protect cholesterol and oil fed cockerels against coronary atherogenesis.

• It has been demonstrated that thyroid hormone and its analogues reduce plasma cholesterol levels both in hypoand in euthyroid individuals; and also that D-thyroxine is much less toxic and less calorigenic than L-thyroxine. Katz and Pick reported that thyroid hormone given to chicks on an atherogenic diet, either as desiccated thyroid or thyroxine, suppressed hypercholesterolemia, but the effe...

Failure off D- and L-Thyroxine to Protect Cholesterol and Oil Fed Cockerels Against Coronary Atherogenesis

• It has been demonstrated that thyroid hormone and its analogues reduce plasma cholesterol levels both in hypoand in euthyroid individuals; and also that D-thyroxine is much less toxic and less calorigenic than L-thyroxine. Katz and Pick reported that thyroid hormone given to chicks on an atherogenic diet, either as desiccated thyroid or thyroxine, suppressed hypercholesterolemia, but the effe...

Aiidrojjen Inhibition of Atherogenesis in Pullets

THE higher incidence of coronary atherosclerosis in young male as compared with young female humans is well established as are similar sex differences in susceptibility in some other species. The administration of female sex hormones to cholesterol-fed cockerels has been reported to have beneficial prophylactic as well as therapeutic effects on coronary atherosclerosis. In one study reported by...

Effect of hypothyroidism on estrogen-induced inhibition of coronary atherogenesis in cholesterol-fed cockerels.

Effects of dietary proteins, methionine and vitamins on plasma lipids and atherogenesis in cholesterol-fed cockerels.

Methionine deficiency in the presence of a high-fat, high-cholesterol diet aggravates atherogenesis in the cockerel. High-protein, high-vitamin supplementation suppresses the atherogenic effect of a cholesterol-fat-containiiig diet. High-protein supplementation alone had a suppressive effect; high-vitamin supplementation had no effect. However, the combined protein and vitamin supplement was th...